DeepUMQA: ultrafast shape recognition-based protein model quality assessment using deep learning.

Journal: Bioinformatics (Oxford, England)
Published Date:

Abstract

MOTIVATION: Protein model quality assessment is a key component of protein structure prediction. In recent research, the voxelization feature was used to characterize the local structural information of residues, but it may be insufficient for describing residue-level topological information. Design features that can further reflect residue-level topology when combined with deep learning methods are therefore crucial to improve the performance of model quality assessment.

Authors

  • Sai-Sai Guo
    College of Information Engineering, Zhejiang University of Technology, Hangzhou 310023, China.
  • Jun Liu
    Department of Radiology, Second Xiangya Hospital, Changsha, Hunan, China.
  • Xiao-Gen Zhou
  • Gui-Jun Zhang