An AI-assisted cryo-EM pipeline for structural studies of cellular extracts.
Journal:
Structure (London, England : 1993)
Published Date:
Apr 7, 2022
Abstract
Proteins, the building blocks of life, often form large assemblies to perform their function but are traditionally studied separately in structural biology. In this issue of Structure, Skalidis et al. (2022) present a workflow to identify members of intact protein communities and solve their structures de novo to near-atomic resolution.