Deep learning for image-based liver analysis - A comprehensive review focusing on malignant lesions.

Journal: Artificial intelligence in medicine
Published Date:

Abstract

Deep learning-based methods, in particular, convolutional neural networks and fully convolutional networks are now widely used in the medical image analysis domain. The scope of this review focuses on the analysis using deep learning of focal liver lesions, with a special interest in hepatocellular carcinoma and metastatic cancer; and structures like the parenchyma or the vascular system. Here, we address several neural network architectures used for analyzing the anatomical structures and lesions in the liver from various imaging modalities such as computed tomography, magnetic resonance imaging and ultrasound. Image analysis tasks like segmentation, object detection and classification for the liver, liver vessels and liver lesions are discussed. Based on the qualitative search, 91 papers were filtered out for the survey, including journal publications and conference proceedings. The papers reviewed in this work are grouped into eight categories based on the methodologies used. By comparing the evaluation metrics, hybrid models performed better for both the liver and the lesion segmentation tasks, ensemble classifiers performed better for the vessel segmentation tasks and combined approach performed better for both the lesion classification and detection tasks. The performance was measured based on the Dice score for the segmentation, and accuracy for the classification and detection tasks, which are the most commonly used metrics.

Authors

  • Shanmugapriya Survarachakan
    Department of Computer Science, Norwegian University of Science and Technology, 7491 Trondheim, Norway. Electronic address: shanmugapriya.survarachakan@ntnu.no.
  • Pravda Jith Ray Prasad
    The Intervention Centre, Oslo University Hospital, 0372 Oslo, Norway; Department of Informatics, University of Oslo, 0315 Oslo, Norway.
  • Rabia Naseem
    Department of Computer Science, Norwegian University of Science and Technology, 2815 Gjøvik, Norway.
  • Javier Pérez de Frutos
    Department of Health Research, SINTEF A.S., 7030 Trondheim, Norway.
  • Rahul Prasanna Kumar
    The Intervention Centre, Oslo University Hospital, 0372 Oslo, Norway.
  • Thomas Langø
  • Faouzi Alaya Cheikh
    Department of Computer Science, Norwegian University of Science and Technology, 2815 Gjøvik, Norway.
  • Ole Jakob Elle
    The Intervention Centre, Oslo University Hospital, 0372 Oslo, Norway; Department of Informatics, University of Oslo, 0315 Oslo, Norway.
  • Frank Lindseth