DXM-TransFuse U-net: Dual cross-modal transformer fusion U-net for automated nerve identification.

Journal: Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Published Date:

Abstract

Accurate nerve identification is critical during surgical procedures to prevent damage to nerve tissues. Nerve injury can cause long-term adverse effects for patients, as well as financial overburden. Birefringence imaging is a noninvasive technique derived from polarized images that have successfully identified nerves that can assist during intraoperative surgery. Furthermore, birefringence images can be processed under 20 ms with a GPGPU implementation, making it a viable image modality option for real-time processing. In this study, we first comprehensively investigate the usage of birefringence images combined with deep learning, which can automatically detect nerves with gains upwards of 14% over its color image-based (RGB) counterparts on the F2 score. Additionally, we develop a deep learning network framework using the U-Net architecture with a Transformer based fusion module at the bottleneck that leverages both birefringence and RGB modalities. The dual-modality framework achieves 76.12 on the F2 score, a gain of 19.6 % over single-modality networks using only RGB images. By leveraging and extracting the feature maps of each modality independently and using each modality's information for cross-modal interactions, we aim to provide a solution that would further increase the effectiveness of imaging systems for enabling noninvasive intraoperative nerve identification.

Authors

  • Baijun Xie
    Department of Biomedical Engineering, School of Engineering and Applied Science, The George Washington University, 800 22nd Street NW, Science & Engineering Hall Suite 5000, Washington 20052, DC, USA.
  • Gary Milam
    Department of Biomedical Engineering, School of Engineering and Applied Science, The George Washington University, 800 22nd Street NW, Science & Engineering Hall Suite 5000, Washington 20052, DC, USA.
  • Bo Ning
    Department of Paediatric Orthopedics, Children's Hospital of Fudan University, Shanghai, China.
  • Jaepyeong Cha
    Children's National Hospital, 111 Michigan Avenue NW, Washington 20010, DC, USA.
  • Chung Hyuk Park