Contemporary Challenges in Clinical Flow Cytometry: Small Samples, Big Data, Little Time.

Journal: The journal of applied laboratory medicine
Published Date:

Abstract

BACKGROUND: Immunophenotypic analysis of cell populations by flow cytometry has an established role in primary diagnosis and disease monitoring of many hematologic diseases. A persistent problem in evaluation of specimens is suboptimal cell counts and low cell viability, which results in an undesirable rate of analysis failure. In addition, the increased amount of data generated in flow cytometry challenges existing data analysis and reporting paradigms.

Authors

  • Jonathan R Brestoff
    Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.
  • John L Frater
    Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.