DCSE:Double-Channel-Siamese-Ensemble model for protein protein interaction prediction.

Journal: BMC genomics
Published Date:

Abstract

BACKGROUND: Protein-protein interaction (PPI) is very important for many biochemical processes. Therefore, accurate prediction of PPI can help us better understand the role of proteins in biochemical processes. Although there are many methods to predict PPI in biology, they are time-consuming and lack accuracy, so it is necessary to build an efficiently and accurately computational model in the field of PPI prediction.

Authors

  • Wenqi Chen
    College of Computer Science and technology, China University of Petroleum (East China), Qingdao, China.
  • Shuang Wang
    Engineering Technology Research Center of Shanxi Province for Opto-Electric Information and Instrument, Taiyuan 030051, China. S1507038@st.nuc.edu.cn.
  • Tao Song
    Department of Cleft Lip and Palate, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing.
  • Xue Li
    Department of Clinical Research Center, Dazhou Central Hospital, Dazhou 635000, China.
  • Peifu Han
    College of Computer Science and technology, China University of Petroleum (East China), Qingdao, China.
  • Changnan Gao
    College of Computer Science and Technology, China University of Petroleum (East China), Qingdao, China.