RAPPPID: towards generalizable protein interaction prediction with AWD-LSTM twin networks.
Journal:
Bioinformatics (Oxford, England)
Published Date:
Aug 10, 2022
Abstract
MOTIVATION: Computational methods for the prediction of protein-protein interactions (PPIs), while important tools for researchers, are plagued by challenges in generalizing to unseen proteins. Datasets used for modelling protein-protein predictions are particularly predisposed to information leakage and sampling biases.