Highly accelerated MR parametric mapping by undersampling the k-space and reducing the contrast number simultaneously with deep learning.

Journal: Physics in medicine and biology
Published Date:

Abstract

To propose a novel deep learning-based method called RG-Net (reconstruction and generation network) for highly accelerated MR parametric mapping by undersampling k-space and reducing the acquired contrast number simultaneously.The proposed framework consists of a reconstruction module and a generative module. The reconstruction module reconstructs MR images from the acquired few undersampled k-space data with the help of a data prior. The generative module then synthesizes the remaining multi-contrast images from the reconstructed images, where the exponential model is implicitly incorporated into the image generation through the supervision of fully sampled labels. The RG-Net was trained and tested on the Tmapping data from 8 volunteers at net acceleration rates of 17, respectively. Regional Tanalysis for cartilage and the brain was performed to assess the performance of RG-Net.RG-Net yields a high-quality Tmap at a high acceleration rate of 17. Compared with the competing methods that only undersample k-space, our framework achieves better performance in Tvalue analysis.The proposed RG-Net can achieve a high acceleration rate while maintaining good reconstruction quality by undersampling k-space and reducing the contrast number simultaneously for fast MR parametric mapping. The generative module of our framework can also be used as an insertable module in other fast MR parametric mapping methods.

Authors

  • Shaonan Liu
    Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China.
  • Haoxiang Li
    Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Shenzhen 518055, People's Republic of China.
  • Yuanyuan Liu
    College of Computer Science and Technology, Chongqing University of Posts and Telecommunications, Chongqing 400065, China.
  • Guanxun Cheng
    Peking University Shenzhen Hospital, Peking University, Shenzhen, Guangdong, People's Republic of China.
  • Gang Yang
    Division of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China.
  • Haifeng Wang
    Collaborative Innovation Center of Seafood Deep Processing, Institute of Seafood, Zhejiang Gongshang University, Hangzhou, 310012, China.
  • Hairong Zheng
    Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055 China.
  • Dong Liang
    Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055 China.
  • Yanjie Zhu
    Paul C. Lauterbur Research Centre for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Shenzhen, Guangdong, China.