IIFDTI: predicting drug-target interactions through interactive and independent features based on attention mechanism.

Journal: Bioinformatics (Oxford, England)
Published Date:

Abstract

MOTIVATION: Identifying drug-target interactions is a crucial step for drug discovery and design. Traditional biochemical experiments are credible to accurately validate drug-target interactions. However, they are also extremely laborious, time-consuming and expensive. With the collection of more validated biomedical data and the advancement of computing technology, the computational methods based on chemogenomics gradually attract more attention, which guide the experimental verifications.

Authors

  • Zhongjian Cheng
  • Qichang Zhao
    School of Computer Science and Engineering, Central South University, China.
  • Yaohang Li
  • Jianxin Wang