Document-Level Chemical-Induced Disease Relation Extraction via Hierarchical Representation Learning.

Journal: IEEE/ACM transactions on computational biology and bioinformatics
Published Date:

Abstract

Over the past decades, Chemical-induced Disease (CID) relations have attracted extensive attention in biomedical community, reflecting wide applications in biomedical research and healthcare field. However, prior efforts fail to make full use of the interaction between local and global contexts in biomedical document, and the derived performance needs to be improved accordingly. In this paper, we propose a novel framework for document-level CID relation extraction. More specifically, a stacked Hypergraph Aggregation Neural Network (HANN) layers are introduced to model the complicated interaction between local and global contexts, based on which better contextualized representations are obtained for CID relation extraction. In addition, the CID Relation Heterogeneous Graph is constructed to capture the information with different granularities and improve further the performance of CID relation classification. Experiments on a real-world dataset demonstrate the effectiveness of the proposed framework.

Authors

  • Weizhong Zhao
    College of Information Engineering, Xiangtan University, Xiangtan, Hunan Province, China; Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, Jefferson, Arkansas, United States of America.
  • Jinyong Zhang
  • Jincai Yang
  • Xingpeng Jiang
    School of Computer, Central China Normal University, Wuhan, Hubei, China. xpjiang@mail.ccnu.edu.cn.
  • Tingting He