Deep learning methods hold promise for light fluence compensation in three-dimensional optoacoustic imaging.

Journal: Journal of biomedical optics
Published Date:

Abstract

SIGNIFICANCE: Quantitative optoacoustic imaging (QOAI) continues to be a challenge due to the influence of nonlinear optical fluence distribution, which distorts the optoacoustic image representation. Nonlinear optical fluence correction in OA imaging is highly ill-posed, leading to the inaccurate recovery of optical absorption maps. This work aims to recover the optical absorption maps using deep learning (DL) approach by correcting for the fluence effect.

Authors

  • Arumugaraj Madasamy
    Indian Institute of Science, Department of Instrumentation and Applied Physics, Bengaluru, Karnataka, India, India.
  • Vipul Gujrati
    Institute of Biological and Medical Imaging, Helmholtz Zentrum München (GmbH), Neuherberg, Germany, Germany.
  • Vasilis Ntziachristos
    Institute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, Germany.
  • Jaya Prakash