Modeling the transplacental transfer of small molecules using machine learning: a case study on per- and polyfluorinated substances (PFAS).

Journal: Journal of exposure science & environmental epidemiology
Published Date: Oct 7, 2022

Abstract

BACKGROUND: Despite their large numbers and widespread use, very little is known about the extent to which per- and polyfluoroalkyl substances (PFAS) can cross the placenta and expose the developing fetus.

Authors

  • Dimitri Abrahamsson
    Program on Reproductive Health and the Environment, Department of Obstetrics and Gynecology, University of California, San Francisco, California 94158, United States.
  • Adi Siddharth
    Department of Obstetrics, Gynecology and Reproductive Sciences, Program on Reproductive Health and the Environment, University of California, San Francisco, 490 Illinois Street, San Francisco, CA, 94143, USA.
  • Joshua F Robinson
    Department of Obstetrics, Gynecology and Reproductive Sciences, Program on Reproductive Health and the Environment, University of California, San Francisco, 490 Illinois Street, San Francisco, CA, 94143, USA.
  • Anatoly Soshilov
    California Environmental Protection Agency, Office of Environmental Health Hazard Assessment, 1001 I St, Sacramento, CA, 95814, USA.
  • Sarah Elmore
    California Environmental Protection Agency, Office of Environmental Health Hazard Assessment, 1001 I St, Sacramento, CA, 95814, USA.
  • Vincent Cogliano
    California Environmental Protection Agency, Office of Environmental Health Hazard Assessment, 1001 I St, Sacramento, CA, 95814, USA.
  • Carla Ng
    Department of Civil and Environmental Engineering, University of Pittsburgh, 3700 O'Hara St, Pittsburgh, PA, 15261, USA.
  • Elaine Khan
    California Environmental Protection Agency, Office of Environmental Health Hazard Assessment, 1001 I St, Sacramento, CA, 95814, USA.
  • Randolph Ashton
    Wisconsin Institute for Discovery, University of Wisconsin, Madison, 330 N Orchard St, Madison, WI, 53715, USA.
  • Weihsueh A Chiu
    Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
  • Jennifer Fung
    Department of Obstetrics, Gynecology, and Reproductive Science and the Center of Reproductive Science, University of California, San Francisco, San Francisco, CA, 94143-2240, USA.
  • Lauren Zeise
    California Environmental Protection Agency, Office of Environmental Health Hazard Assessment, 1001 I St, Sacramento, CA, 95814, USA.
  • Tracey J Woodruff
    Program on Reproductive Health and the Environment, Department of Obstetrics and Gynecology, University of California, San Francisco, California 94158, United States.

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