Multi-modality artificial intelligence in digital pathology.

Journal: Briefings in bioinformatics
Published Date:

Abstract

In common medical procedures, the time-consuming and expensive nature of obtaining test results plagues doctors and patients. Digital pathology research allows using computational technologies to manage data, presenting an opportunity to improve the efficiency of diagnosis and treatment. Artificial intelligence (AI) has a great advantage in the data analytics phase. Extensive research has shown that AI algorithms can produce more up-to-date and standardized conclusions for whole slide images. In conjunction with the development of high-throughput sequencing technologies, algorithms can integrate and analyze data from multiple modalities to explore the correspondence between morphological features and gene expression. This review investigates using the most popular image data, hematoxylin-eosin stained tissue slide images, to find a strategic solution for the imbalance of healthcare resources. The article focuses on the role that the development of deep learning technology has in assisting doctors' work and discusses the opportunities and challenges of AI.

Authors

  • Yixuan Qiao
    Operations Research and Cybernetics at Beijing University of Technology, China.
  • Lianhe Zhao
    Research Center for Ubiquitous Computing Systems, Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100190, China.
  • Chunlong Luo
  • Yufan Luo
    Division of Systems Engineering, Boston University, Boston, MA 02215, USA. Electronic address: luoyuf@bu.edu.
  • Yang Wu
  • Shengtong Li
    Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Dechao Bu
    Research Center for Ubiquitous Computing Systems, Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100190, China.
  • Yi Zhao
    Department of Biostatistics and Health Data Science, Indiana University School of Medicine.