Development and evaluation of deep learning algorithms for assessment of acute burns and the need for surgery.

Journal: Scientific reports
Published Date:

Abstract

Assessment of burn extent and depth are critical and require very specialized diagnosis. Automated image-based algorithms could assist in performing wound detection and classification. We aimed to develop two deep-learning algorithms that respectively identify burns, and classify whether they require surgery. An additional aim assessed the performances in different Fitzpatrick skin types. Annotated burn (n = 1105) and background (n = 536) images were collected. Using a commercially available platform for deep learning algorithms, two models were trained and validated on 70% of the images and tested on the remaining 30%. Accuracy was measured for each image using the percentage of wound area correctly identified and F1 scores for the wound identifier; and area under the receiver operating characteristic (AUC) curve, sensitivity, and specificity for the wound classifier. The wound identifier algorithm detected an average of 87.2% of the wound areas accurately in the test set. For the wound classifier algorithm, the AUC was 0.885. The wound identifier algorithm was more accurate in patients with darker skin types; the wound classifier was more accurate in patients with lighter skin types. To conclude, image-based algorithms can support the assessment of acute burns with relatively good accuracy although larger and different datasets are needed.

Authors

  • Constance Boissin
    Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden. constance.boissin@ki.se.
  • Lucie Laflamme
    Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
  • Jian Fransén
    Department of Plastic and Maxillofacial Surgery, Burn Center, Uppsala University Hospital, Uppsala, Sweden.
  • Mikael Lundin
    Institute for Molecular Medicine Finland, HILIFE, University of Helsinki, Helsinki, Finland.
  • Fredrik Huss
    Department of Plastic and Maxillofacial Surgery, Burn Center, Uppsala University Hospital, Uppsala, Sweden.
  • Lee Wallis
    Division of Emergency Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Bellville, South Africa.
  • Nikki Allorto
    Pietermaritzburg Burn Service, Department of General Surgery, University of Kwa-Zulu Natal, Pietermaritzburg, South Africa.
  • Johan Lundin
    Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.