Semi-supervised automatic dental age and sex estimation using a hybrid transformer model.

Journal: International journal of legal medicine
PMID:

Abstract

Teeth-based age and sex estimation is an important task in mass disasters, criminal scenes, and archeology. Although various methods have been proposed, most of them are subjective and influenced by observers' experiences. In this study, we aimed to develop a deep learning model for automatic dental age and sex estimation from orthopantomograms (OPGs) and compare to manual methods. A large dataset of 15,195 OPGs (age range, 16 ~ 50 years; mean age, 29.65 years ± 9.36 [SD]; 10,218 females) was used to train and test a hybrid deep learning model which is a combination of convolutional neural network and transformer model. The final performance of this model was evaluated on additional independent 100 OPGs and compared to the manual method for external validation. In the test of 1413 OPGs, the mean absolute error (MAE) of age estimation was 2.61 years by this model. The accuracy and the area under the receiver operating characteristic curve (AUC) of sex estimation were 95.54% and 0.984. The heatmap indicated that the crown and pulp chamber of premolars and molars contain the most age-related information. In the additional independent 100 OPGs, this model achieved an MAE of 3.28 years for males and 3.79 years for females. The accuracy of this model was much higher than that of the manual models. Therefore, this model has the potential to assist radiologists in automated age and sex estimation.

Authors

  • Fei Fan
    West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
  • Wenchi Ke
    College of Computer Science, Sichuan University, Chengdu 610064, China.
  • Xinhua Dai
    West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
  • Lei Shi
  • Yuanyuan Liu
    College of Computer Science and Technology, Chongqing University of Posts and Telecommunications, Chongqing 400065, China.
  • Yushan Lin
    West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, No.17 People's South Road, Chengdu, 610041, People's Republic of China.
  • Ziqi Cheng
    West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, No.17 People's South Road, Chengdu, 610041, People's Republic of China.
  • Yi Zhang
    Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Jilin University, Changchun, China.
  • Hu Chen
  • Zhenhua Deng
    Department of Forensic Pathology, West China School of Preclinical and Forensic Medicine, Sichuan University, No. three, 17 South Renmin Road, Wuhou District, Chengdu City, 610041, Sichuan, People's Republic of China. fydzh63@163.com.