Deep Learning Reconstruction Enables Prospectively Accelerated Clinical Knee MRI.

Journal: Radiology
Published Date:

Abstract

Background MRI is a powerful diagnostic tool with a long acquisition time. Recently, deep learning (DL) methods have provided accelerated high-quality image reconstructions from undersampled data, but it is unclear if DL image reconstruction can be reliably translated to everyday clinical practice. Purpose To determine the diagnostic equivalence of prospectively accelerated DL-reconstructed knee MRI compared with conventional accelerated MRI for evaluating internal derangement of the knee in a clinical setting. Materials and Methods A DL reconstruction model was trained with images from 298 clinical 3-T knee examinations. In a prospective analysis, patients clinically referred for knee MRI underwent a conventional accelerated knee MRI protocol at 3 T followed by an accelerated DL protocol between January 2020 and February 2021. The equivalence of the DL reconstruction of the images relative to the conventional images for the detection of an abnormality was assessed in terms of interchangeability. Each examination was reviewed by six musculoskeletal radiologists. Analyses pertaining to the detection of meniscal or ligament tears and bone marrow or cartilage abnormalities were based on four-point ordinal scores for the likelihood of an abnormality. Additionally, the protocols were compared with use of four-point ordinal scores for each aspect of image quality: overall image quality, presence of artifacts, sharpness, and signal-to-noise ratio. Results A total of 170 participants (mean age ± SD, 45 years ± 16; 76 men) were evaluated. The DL-reconstructed images were determined to be of diagnostic equivalence with the conventional images for detection of abnormalities. The overall image quality score, averaged over six readers, was significantly better ( < .001) for the DL than for the conventional images. Conclusion In a clinical setting, deep learning reconstruction enabled a nearly twofold reduction in scan time for a knee MRI and was diagnostically equivalent with the conventional protocol. © RSNA, 2023 See also the editorial by Roemer in this issue.

Authors

  • Patricia M Johnson
    Imaging Research Laboratories, Robarts Research Institute, The University of Western Ontario, London, Ontario, Canada.
  • Dana J Lin
    Division of Musculoskeletal Radiology, Department of Radiology, NYU Langone Health, New York, New York.
  • Jure Zbontar
    Facebook Artificial Intelligence Research, New York, NY.
  • C Lawrence Zitnick
    Facebook Artificial Intelligence Research, Menlo Park, CA.
  • Anuroop Sriram
    Facebook Artificial Intelligence Research, Menlo Park, CA.
  • Matthew Muckley
    Facebook Artificial Intelligence Research, New York, NY.
  • James S Babb
    Department of Radiology (M.K., W.M., K.F., J.S.B., G.M., J.P.K.), Department of Medicine, Division of Hematology and Medical Oncology, Laura and Isaac Perlmutter Cancer Center (D.K.), and Center for Healthcare Innovation and Delivery Science (L.I.H.), NYU Langone Health, 550 First Ave, New York, NY 10016; Division of Healthcare Delivery Science, Department of Population Health and Division of General Internal Medicine and Clinical Innovation, Department of Medicine, NYU Grossman School of Medicine, New York, NY (L.I.H.); and Garden State Urology, Wayne, NJ (A.K.).
  • Mitchell Kline
    Department of Radiology, New York University Grossman School of Medicine, 660 First Ave, 3rd Fl, New York, NY 10016.
  • Gina Ciavarra
    Department of Radiology, New York University Grossman School of Medicine, 660 First Ave, 3rd Fl, New York, NY 10016.
  • Erin Alaia
    From the Department of Radiology, New York University Grossman School of Medicine, 650 1st Ave, New York, NY 10016 (P.M.J., D.J.L., J.S.B., M.K., G.C., E.A., M.S., W.R.W., L.C., D.K.S., M.P.R., F.K.); Meta AI Research (FAIR), Menlo Park, Calif (J.Z., C.L.Z., A.S.); Meta AI Research, New York, NY (M.M.); Institute of Computer Graphics and Vision, Graz University of Technology, Graz, Austria (T.P.); and Faculty of Engineering, Friedrich Alexander University Erlangen-Nurnberg (FAU), Erlangen, Germany (F.K.).
  • Mohammad Samim
    Department of Radiology, New York University Grossman School of Medicine, 660 First Ave, 3rd Fl, New York, NY 10016.
  • William R Walter
    Department of Radiology, New York University Grossman School of Medicine, 660 First Ave, 3rd Fl, New York, NY 10016.
  • Liz Calderon
    From the Department of Radiology, New York University Grossman School of Medicine, 650 1st Ave, New York, NY 10016 (P.M.J., D.J.L., J.S.B., M.K., G.C., E.A., M.S., W.R.W., L.C., D.K.S., M.P.R., F.K.); Meta AI Research (FAIR), Menlo Park, Calif (J.Z., C.L.Z., A.S.); Meta AI Research, New York, NY (M.M.); Institute of Computer Graphics and Vision, Graz University of Technology, Graz, Austria (T.P.); and Faculty of Engineering, Friedrich Alexander University Erlangen-Nurnberg (FAU), Erlangen, Germany (F.K.).
  • Thomas Pock
    Institute of Computer Graphics and Vision, Graz University of Technology, Graz, Austria.
  • Daniel K Sodickson
    Center for Biomedical Imaging, Department of Radiology, NYU School of Medicine, New York, New York, USA.
  • Michael P Recht
    Center for Biomedical Imaging, Department of Radiology, NYU School of Medicine, New York, New York, USA.
  • Florian Knoll
    Center for Biomedical Imaging, Department of Radiology, NYU School of Medicine, New York, New York, USA.