Artificial intelligence and machine learning overview in pathology & laboratory medicine: A general review of data preprocessing and basic supervised concepts.

Journal: Seminars in diagnostic pathology
Published Date:

Abstract

Machine learning (ML) is becoming an integral aspect of several domains in medicine. Yet, most pathologists and laboratory professionals remain unfamiliar with such tools and are unprepared for their inevitable integration. To bridge this knowledge gap, we present an overview of key elements within this emerging data science discipline. First, we will cover general, well-established concepts within ML, such as data type concepts, data preprocessing methods, and ML study design. We will describe common supervised and unsupervised learning algorithms and their associated common machine learning terms (provided within a comprehensive glossary of terms that are discussed within this review). Overall, this review will offer a broad overview of the key concepts and algorithms in machine learning, with a focus on pathology and laboratory medicine. The objective is to provide an updated useful reference for those new to this field or those who require a refresher.

Authors

  • Samer Albahra
    Pathology & Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio.
  • Tom Gorbett
    Pathology and Laboratory Medicine Institute (PLMI), Cleveland Clinic, Cleveland, OH, United States; PLMI's Center for Artificial Intelligence & Data Science, Cleveland Clinic, Cleveland, OH, United States.
  • Scott Robertson
    Pathology and Laboratory Medicine Institute (PLMI), Cleveland Clinic, Cleveland, OH, United States; PLMI's Center for Artificial Intelligence & Data Science, Cleveland Clinic, Cleveland, OH, United States.
  • Giana D'Aleo
    Pathology and Laboratory Medicine Institute (PLMI), Cleveland Clinic, Cleveland, OH, United States; PLMI's Center for Artificial Intelligence & Data Science, Cleveland Clinic, Cleveland, OH, United States.
  • Sushasree Vasudevan Suseel Kumar
    Pathology and Laboratory Medicine Institute (PLMI), Cleveland Clinic, Cleveland, OH, United States; PLMI's Center for Artificial Intelligence & Data Science, Cleveland Clinic, Cleveland, OH, United States.
  • Samuel Ockunzzi
    Pathology and Laboratory Medicine Institute (PLMI), Cleveland Clinic, Cleveland, OH, United States; PLMI's Center for Artificial Intelligence & Data Science, Cleveland Clinic, Cleveland, OH, United States.
  • Daniel Lallo
    Pathology and Laboratory Medicine Institute (PLMI), Cleveland Clinic, Cleveland, OH, United States; PLMI's Center for Artificial Intelligence & Data Science, Cleveland Clinic, Cleveland, OH, United States.
  • Bo Hu
    Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
  • Hooman H Rashidi
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Computational Pathology and AI Center of Excellence (CPACE), University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Electronic address: rashidihh@upmc.edu.