AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research.

Journal: PLoS biology
Published Date: Feb 8, 2023

Abstract

In this issue of PLOS Biology, Ibrahim and colleagues demonstrate how AlphaFold-multimer, an artificial intelligence-based structure prediction tool, can be used to identify sequence motifs binding to the ATG8 family of proteins central to autophagy.

Authors

  • Hallvard Lauritz Olsvik
    Autophagy Research Group, Department of Medical Biology, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
  • Terje Johansen
    Autophagy Research Group, Department of Medical Biology, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.

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