Joint learning-based causal relation extraction from biomedical literature.

Journal: Journal of biomedical informatics
PMID:

Abstract

Causal relation extraction of biomedical entities is one of the most complex tasks in biomedical text mining, which involves two kinds of information: entity relations and entity functions. One feasible approach is to take relation extraction and function detection as two independent sub-tasks. However, this separate learning method ignores the intrinsic correlation between them and leads to unsatisfactory performance. In this paper, we propose a joint learning model, which combines entity relation extraction and entity function detection to exploit their commonality and capture their inter-relationship, so as to improve the performance of biomedical causal relation extraction. Experimental results on the BioCreative-V Track 4 corpus show that our joint learning model outperforms the separate models in BEL statement extraction, achieving the F1 scores of 57.0% and 37.3% on the test set in Stage 2 and Stage 1 evaluations, respectively. This demonstrates that our joint learning system reaches the state-of-the-art performance in Stage 2 compared with other systems.

Authors

  • Dongling Li
    State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China; Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
  • Pengchao Wu
    School of Computer Science and Technology, Soochow University, Suzhou, Jiangsu Province 215006, China. Electronic address: 20204227037@stu.suda.edu.cn.
  • Yuehu Dong
    School of Computer Science and Technology, Soochow University, Suzhou, Jiangsu Province 215006, China. Electronic address: 20215227045@stu.suda.edu.cn.
  • Jinghang Gu
    School of Computer Science and Technology, Soochow University, 1 Shizi Street, Suzhou, China.
  • Longhua Qian
    School of Computer Science and Technology, Soochow University, 1 Shizi Street, Suzhou, China.
  • Guodong Zhou
    School of Computer Science and Technology, Soochow University, 1 Shizi Street, Suzhou, China.