CNN-Siam: multimodal siamese CNN-based deep learning approach for drug‒drug interaction prediction.
Journal:
BMC bioinformatics
Published Date:
Mar 23, 2023
Abstract
BACKGROUND: Drug‒drug interactions (DDIs) are reactions between two or more drugs, i.e., possible situations that occur when two or more drugs are used simultaneously. DDIs act as an important link in both drug development and clinical treatment. Since it is not possible to study the interactions of such a large number of drugs using experimental means, a computer-based deep learning solution is always worth investigating. We propose a deep learning-based model that uses twin convolutional neural networks to learn representations from multimodal drug data and to make predictions about the possible types of drug effects.