Multi-event survival analysis through dynamic multi-modal learning for ICU mortality prediction.
Journal:
Computer methods and programs in biomedicine
Published Date:
Apr 11, 2023
Abstract
BACKGROUND AND OBJECTIVE: Survival analysis is widely applied for assessing the expected duration of patient status towards event occurrences such as mortality in healthcare domain, which is generally considered as a time-to-event problem. Patients with multiple complications have high mortality risks and oftentimes require specific intensive care and clinical treatments. The progression of complications is time-varying according to disease development and intrinsic interactions between complications with respect to mortality are uncertain. Classical methods for mortality prediction and survival analysis in critical care, such as risk scoring systems and cause-specific survival models, were not designed for this multi-event survival analysis problem and able to measure the competing risks of death for mutually exclusive events. In addition, multivariate temporal information of complications is not taken into consideration while estimating differentiated mortality risks in the early stage.