Two-Stage Self-Supervised Cycle-Consistency Transformer Network for Reducing Slice Gap in MR Images.

Journal: IEEE journal of biomedical and health informatics
Published Date:

Abstract

Magnetic resonance (MR) images are usually acquired with large slice gap in clinical practice, i.e., low resolution (LR) along the through-plane direction. It is feasible to reduce the slice gap and reconstruct high-resolution (HR) images with the deep learning (DL) methods. To this end, the paired LR and HR images are generally required to train a DL model in a popular fully supervised manner. However, since the HR images are hardly acquired in clinical routine, it is difficult to get sufficient paired samples to train a robust model. Moreover, the widely used convolutional Neural Network (CNN) still cannot capture long-range image dependencies to combine useful information of similar contents, which are often spatially far away from each other across neighboring slices. To this end, a Two-stage Self-supervised Cycle-consistency Transformer Network (TSCTNet) is proposed to reduce the slice gap for MR images in this work. A novel self-supervised learning (SSL) strategy is designed with two stages respectively for robust network pre-training and specialized network refinement based on a cycle-consistency constraint. A hybrid Transformer and CNN structure is utilized to build an interpolation model, which explores both local and global slice representations. The experimental results on two public MR image datasets indicate that TSCTNet achieves superior performance over other compared SSL-based algorithms.

Authors

  • Zhiyang Lu
  • Jian Wang
    Veterinary Diagnostic Center, Shanghai Animal Disease Control Center, Shanghai, China.
  • Zheng Li
    Department of Integrated Pulmonology, Fourth Clinical Medical College of Xinjiang Medical University, Urumqi, Xinjiang, China.
  • Shihui Ying
    Department of Mathematics, School of Science, Shanghai University, China. Electronic address: shying@shu.edu.cn.
  • Jun Wang
    Department of Speech, Language, and Hearing Sciences and the Department of Neurology, The University of Texas at Austin, Austin, TX 78712, USA.
  • Jun Shi
    School of Communication and Information Engineering, Shanghai University, Shanghai, China. Electronic address: junshi@staff.shu.edu.cn.
  • Dinggang Shen
    School of Biomedical Engineering, ShanghaiTech University, Shanghai, China.