Deep Learning Segmentation of the Right Ventricle in Cardiac MRI: The M&Ms Challenge.

Journal: IEEE journal of biomedical and health informatics
Published Date:

Abstract

In recent years, several deep learning models have been proposed to accurately quantify and diagnose cardiac pathologies. These automated tools heavily rely on the accurate segmentation of cardiac structures in MRI images. However, segmentation of the right ventricle is challenging due to its highly complex shape and ill-defined borders. Hence, there is a need for new methods to handle such structure's geometrical and textural complexities, notably in the presence of pathologies such as Dilated Right Ventricle, Tricuspid Regurgitation, Arrhythmogenesis, Tetralogy of Fallot, and Inter-atrial Communication. The last MICCAI challenge on right ventricle segmentation was held in 2012 and included only 48 cases from a single clinical center. As part of the 12th Workshop on Statistical Atlases and Computational Models of the Heart (STACOM 2021), the M&Ms-2 challenge was organized to promote the interest of the research community around right ventricle segmentation in multi-disease, multi-view, and multi-center cardiac MRI. Three hundred sixty CMR cases, including short-axis and long-axis 4-chamber views, were collected from three Spanish hospitals using nine different scanners from three different vendors, and included a diverse set of right and left ventricle pathologies. The solutions provided by the participants show that nnU-Net achieved the best results overall. However, multi-view approaches were able to capture additional information, highlighting the need to integrate multiple cardiac diseases, views, scanners, and acquisition protocols to produce reliable automatic cardiac segmentation algorithms.

Authors

  • Carlos Martín-Isla
    Dept. de Matemàtiques i Informàtica, Universitat de Barcelona, Spain.
  • Víctor M Campello
    Dept. de Matemàtiques i Informàtica, Universitat de Barcelona, Spain.
  • Cristian Izquierdo
  • Kaisar Kushibar
    Institute of Computer Vision and Robotics, University of Girona, Ed. P-IV, Campus Montilivi, Girona, 17003, Spain. Electronic address: kaisar.kushibar@udg.edu.
  • Carla Sendra-Balcells
    Dept. de Matemàtiques i Informàtica, Universitat de Barcelona, Spain. Electronic address: carla.sendra@ub.edu.
  • Polyxeni Gkontra
    Biomedical Imaging Research Group (GIBI230), La Fe Health Research Institute, Av. Fernando Abril Martorell 106, Torre E, 46026, Valencia, Spain.
  • Alireza Sojoudi
    Circle Cardiovascular Imaging, Calgary, AB, Canada.
  • Mitchell J Fulton
  • Tewodros Weldebirhan Arega
    ImViA EA 7535 Laboratory, University of Burgundy, 21078 Dijon, France.
  • Kumaradevan Punithakumar
  • Lei Li
    Department of Thoracic Surgery, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, China.
  • Xiaowu Sun
    Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Yasmina Al Khalil
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands. Electronic address: y.al.khalil@tue.nl.
  • Di Liu
    Laboratory of Nutrition and Functional Food, College of Food Science and Engineering, Jilin University, Changchun, China.
  • Sana Jabbar
  • Sandro Queiros
  • Francesco Galati
  • Moona Mazher
  • Zheyao Gao
  • Marcel Beetz
  • Lennart Tautz
  • Christoforos Galazis
    Imperial College London, National Heart & Lung Institute, London, W12 0NN, UK.
  • Marta Varela
    National Heart and Lung Institute, Imperial College London, London, United Kingdom.
  • Markus Hullebrand
  • Vicente Grau
    Department of Engineering Science, University of Oxford, Oxford, United Kingdom.
  • Xiahai Zhuang
    School of Data Science, Fudan University, Shanghai, China; Fudan-Xinzailing Joint Research Center for Big Data, Fudan University, Shanghai, China. Electronic address: zxh@fudan.edu.cn.
  • Domenec Puig
    Department of Computer Engineering and Mathematics, Universitat Rovira i Virgili, Tarragona, 43007, Tarragona, Spain.
  • Maria A Zuluaga
  • Hassan Mohy-Ud-Din
  • Dimitris Metaxas
  • Marcel Breeuwer
    Department of Biomedical Engineering, Medical Image Analysis group, Eindhoven University of Technology, Eindhoven, The Netherlands.
  • Rob J van der Geest
    Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden PO Box 9600, 2300 RC, The Netherlands.
  • Michelle Noga
  • Stéphanie Bricq
    Le2i, Université Bourgogne Franche-Comte, Dijon, France.
  • Mark E Rentschler
    Department of Mechanical Engineering, University of Colorado, Boulder, Colorado, USA.
  • Andrea Guala
    Cardiovascular Imaging Unit, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
  • Steffen E Petersen
    Cardiac Imaging Department, Barts Heart Centre, St Bartholomew's Hospital, London, UK; William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, London, UK.
  • Sergio Escalera
  • Jose F Rodriguez Palomares
  • Karim Lekadir
    Information and Communication Technologies Department, Universitat Pompeu Fabra, Barcelona, Spain.