Untethered shape-changing devices in the gastrointestinal tract.

Journal: Expert opinion on drug delivery
PMID: 38044866

Abstract

INTRODUCTION: Advances in microfabrication, automation, and computer engineering seek to revolutionize small-scale devices and machines. Emerging trends in medicine point to smart devices that emulate the motility, biosensing abilities, and intelligence of cells and pathogens that inhabit the human body. Two important characteristics of smart medical devices are the capability to be deployed in small conduits, which necessitates being untethered, and the capacity to perform mechanized functions, which requires autonomous shape-changing.

Authors

  • Wangqu Liu
    Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, USA.
  • Soo Jin Choi
    Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, USA.
  • Derosh George
    Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, USA.
  • Ling Li
    College of Communication Engineering, Jilin University, Changchun, Jilin China.
  • Zijian Zhong
    Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, USA.
  • Ruili Zhang
    College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China; Key Laboratory of the Provincial Education, Department of Heilongjiang for Common Animal Disease Prevention and Treatment, Northeast Agricultural University, Harbin 150030, China. Electronic address: zhangruili@neau.edu.cn.
  • Si Young Choi
    Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, USA.
  • Florin M Selaru
    Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins School of Medicine, Baltimore, USA.
  • David H Gracias
    Department of Materials Science and Engineering, The Johns Hopkins University, Baltimore, MD, 21218, United States of America.

Keywords

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