Weakly Supervised MRI Slice-Level Deep Learning Classification of Prostate Cancer Approximates Full Voxel- and Slice-Level Annotation: Effect of Increasing Training Set Size.

Journal: Journal of magnetic resonance imaging : JMRI
Published Date:

Abstract

BACKGROUND: Weakly supervised learning promises reduced annotation effort while maintaining performance.

Authors

  • Cedric Weißer
  • Nils Netzer
  • Magdalena Görtz
    Department of Urology, University of Heidelberg Medical Center, Heidelberg, Germany.
  • Viktoria Schütz
    Department of Urology, University of Heidelberg Medical Center, Heidelberg, Germany.
  • Thomas Hielscher
    Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Constantin Schwab
    Institute of Pathology, University of Heidelberg Medical Center.
  • Markus Hohenfellner
    From the Department of Radiology (D.B., P.S., J.P.R., P.K., K.Y., M.F., H.P.S.), Division of Medical Image Computing (S.K., M.G., N.G., K.H.M.H.), Division of Statistics (M.W.), and Department of Medical Physics (T.A.K., F.D.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany (D.B., H.P.S., K.H.M.H.); and Departments of Urology (J.P.R., B.H., M.H., B.A.H.) and Neuroradiology (P.K.), University of Heidelberg Medical Center, Heidelberg, Germany.
  • Heinz-Peter Schlemmer
    From the Department of Radiology (D.B., P.S., J.P.R., P.K., K.Y., M.F., H.P.S.), Division of Medical Image Computing (S.K., M.G., N.G., K.H.M.H.), Division of Statistics (M.W.), and Department of Medical Physics (T.A.K., F.D.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany (D.B., H.P.S., K.H.M.H.); and Departments of Urology (J.P.R., B.H., M.H., B.A.H.) and Neuroradiology (P.K.), University of Heidelberg Medical Center, Heidelberg, Germany.
  • Klaus H Maier-Hein
    Medical Image Computing (MIC), German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: k.maier-hein@dkfz.de.
  • David Bonekamp
    From the Department of Radiology (D.B., P.S., J.P.R., P.K., K.Y., M.F., H.P.S.), Division of Medical Image Computing (S.K., M.G., N.G., K.H.M.H.), Division of Statistics (M.W.), and Department of Medical Physics (T.A.K., F.D.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany (D.B., H.P.S., K.H.M.H.); and Departments of Urology (J.P.R., B.H., M.H., B.A.H.) and Neuroradiology (P.K.), University of Heidelberg Medical Center, Heidelberg, Germany.