A nystagmus extraction system using artificial intelligence for video-nystagmography.

Journal: Scientific reports
Published Date:

Abstract

Benign paroxysmal positional vertigo (BPPV), the most common vestibular disorder, is diagnosed by an examiner changing the posture of the examinee and inducing nystagmus. Among the diagnostic methods used to observe nystagmus, video-nystagmography has been widely used recently because it is non-invasive. A specialist with professional knowledge and training in vertigo diagnosis is needed to diagnose BPPV accurately, but the ratio of vertigo patients to specialists is too high, thus necessitating the need for automated diagnosis of BPPV. In this paper, a convolutional neural network-based nystagmus extraction system, ANyEye, optimized for video-nystagmography data is proposed. A pupil was segmented to track the exact pupil trajectory from real-world data obtained during field inspection. A deep convolutional neural network model was trained with the new video-nystagmography dataset for the pupil segmentation task, and a compensation algorithm was designed to correct pupil position. In addition, a slippage detection algorithm based on moving averages was designed to eliminate the motion artifacts induced by goggle slippage. ANyEye outperformed other eye-tracking methods including learning and non-learning-based algorithms with five-pixel error detection rate of 91.26%.

Authors

  • Yerin Lee
    Department of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, Kangwon-do, Republic of Korea.
  • Sena Lee
    Department of Precision Medicine, Yonsei University Wonju College of Medicine, Wonju, 26426, Republic of Korea.
  • Junghun Han
    Department of Biomedical Engineering, Yonsei University, Wonju, 26493, Republic of Korea.
  • Young Joon Seo
    Research Institute of Hearing Enhancement, Yonsei University Wonju College of Medicine, Wonju, 26426, Republic of Korea. okas2000@yonsei.ac.kr.
  • Sejung Yang
    Medical Physics Division, Department of Radiation Oncology, Stanford University School of Medicine, Palo Alto, United States of America.