Anti-pandemic influenza A (H1N1) virus potential of catechin and gallic acid.

Journal: Journal of the Chinese Medical Association : JCMA
PMID: 29287704

Abstract

BACKGROUND: The pandemic influenza A (H1N1) virus has spread worldwide and infected a large proportion of the human population. Discovery of new and effective drugs for the treatment of influenza is a crucial issue for the global medical community. According to our previous study, TSL-1, a fraction of the aqueous extract from the tender leaf of Toonasinensis, has demonstrated antiviral activities against pandemic influenza A (H1N1) through the down-regulation of adhesion molecules and chemokine to prevent viral attachment.

Authors

  • Huey-Ling You
    Department of Laboratory Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC; Department of Medical Laboratory Sciences and Biotechnology, Fooyin University, Kaohsiung, Taiwan, ROC.
  • Chao-Chun Huang
    Division of General Surgery, Ministry of Health and Welfare Pingtung Hospital, Pingtung, Taiwan, ROC.
  • Chung-Jen Chen
    Division of General Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ROC.
  • Cheng-Chin Chang
    Department of Chinese Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC.
  • Pei-Lin Liao
    Division of Pediatric Surgery and Mitochondrial Research Unit, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, ROC.
  • Sheng-Teng Huang
    Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan; School of Chinese Medicine, China Medical University, Taichung, Taiwan; Research Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan; Chinese Medicine Research Center, China Medical University, Taichung, Taiwan; Research Center for Chinese Herbal Medicine, China Medical University, Taichung, Taiwan; Tainan Municipal An-Nan Hospital, China Medical University, Taichung, Taiwan. Electronic address: d98294@mail.cmuh.org.tw.

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