Tailored multi-organ segmentation with model adaptation and ensemble.

Journal: Computers in biology and medicine
Published Date:

Abstract

Multi-organ segmentation, which identifies and separates different organs in medical images, is a fundamental task in medical image analysis. Recently, the immense success of deep learning motivated its wide adoption in multi-organ segmentation tasks. However, due to expensive labor costs and expertise, the availability of multi-organ annotations is usually limited and hence poses a challenge in obtaining sufficient training data for deep learning-based methods. In this paper, we aim to address this issue by combining off-the-shelf single-organ segmentation models to develop a multi-organ segmentation model on the target dataset, which helps get rid of the dependence on annotated data for multi-organ segmentation. To this end, we propose a novel dual-stage method that consists of a Model Adaptation stage and a Model Ensemble stage. The first stage enhances the generalization of each off-the-shelf segmentation model on the target domain, while the second stage distills and integrates knowledge from multiple adapted single-organ segmentation models. Extensive experiments on four abdomen datasets demonstrate that our proposed method can effectively leverage off-the-shelf single-organ segmentation models to obtain a tailored model for multi-organ segmentation with high accuracy.

Authors

  • Jiahua Dong
    College of Computer Science and Technology, Zhejiang University, Hangzhou, 310027, China.
  • Guohua Cheng
    Institute of Science and Technology for Brain-Inspired Intelligence, Ministry of Education-Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Fudan University, Shanghai, 200433, China.
  • Yue Zhang
    Department of Ophthalmology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
  • Chengtao Peng
    Department of Electronic Science and technology, University of Science and Technology of China, Hefei, 230061, China.
  • Yu Song
    Department of Systems Management, Fukuoka Institute of Technology, Fukuoka, Japan.
  • Ruofeng Tong
    State Key Lab of CAD & CG, Zhejiang University, Hangzhou, 310027, China.
  • Lanfen Lin
    State Key Lab of CAD & CG, Zhejiang University, Hangzhou, 310027, China.
  • Yen-Wei Chen