Limit and screen sequences with high degree of secondary structures in DNA storage by deep learning method.

Journal: Computers in biology and medicine
Published Date: Oct 2, 2023

Abstract

BACKGROUND: In single-stranded DNAs/RNAs, secondary structures are very common especially in long sequences. It has been recognized that the high degree of secondary structures in DNA sequences could interfere with the correct writing and reading of information in DNA storage. However, how to circumvent its side-effect is seldom studied.

Authors

  • Wanmin Lin
    Institute of Computing Science and Technology, Guangzhou University, Guangzhou, Guangdong, China.
  • Ling Chu
    Institute of Computing Science and Technology, Guangzhou University, Guangzhou, Guangdong, China.
  • Yanqing Su
    Institute of Computing Science and Technology, Guangzhou University, Guangzhou, Guangdong, China.
  • Ranze Xie
    Institute of Computing Science and Technology, Guangzhou University, Guangzhou, Guangdong, China.
  • Xiangyu Yao
    Institute of Computing Science and Technology, Guangzhou University, Guangzhou, Guangdong, China.
  • Xiangzhen Zan
    Institute of Computing Science and Technology, Guangzhou University, Guangzhou, Guangdong, China.
  • Peng Xu
    Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Wenbin Liu
    Department of Radiology, Changhai Hospital.

Keywords

External Resources

Popular Topics
Recent Journals