Development and validation of a convolutional neural network to identify blepharoptosis.

Journal: Scientific reports
Published Date:

Abstract

Blepharoptosis is a recognized cause of reversible vision loss and a non-specific indicator of neurological issues, occasionally heralding life-threatening conditions. Currently, diagnosis relies on human expertise and eyelid examination, with most existing Artificial Intelligence algorithms focusing on eyelid positioning under specialized settings. This study introduces a deep learning model with convolutional neural networks to detect blepharoptosis in more realistic conditions. Our model was trained and tested using high quality periocular images from patients with blepharoptosis as well as those with other eyelid conditions. The model achieved an area under the receiver operating characteristic curve of 0.918. For validation, we compared the model's performance against nine medical experts-oculoplastic surgeons, general ophthalmologists, and general practitioners-with varied expertise. When tested on a new dataset with varied image quality, the model's performance remained statistically comparable to that of human graders. Our findings underscore the potential to enhance telemedicine services for blepharoptosis detection.

Authors

  • Cristina Abascal Azanza
    Department of Ophthalmology, Navarra Institute for Health Research (IdiSNA), Clínica Universidad de Navarra, Av. de Pío XII, 36, 31008, Pamplona, Navarra, Spain.
  • Jesús Barrio-Barrio
    Department of Ophthalmology, Navarra Institute for Health Research (IdiSNA), Clínica Universidad de Navarra, Av. de Pío XII, 36, 31008, Pamplona, Navarra, Spain. jbarrio@unav.es.
  • Jaime Ramos Cejudo
    Grossman School of Medicine, New York University (NYU, New York, USA.
  • Bosco Ybarra Arróspide
    Imagine Apps, Madrid, Spain.
  • Martín H Devoto
    Consultores Oftalmologicos, Buenos Aires, Argentina.