Fetal biometry and amniotic fluid volume assessment end-to-end automation using Deep Learning.

Journal: Nature communications
PMID:

Abstract

Fetal biometry and amniotic fluid volume assessments are two essential yet repetitive tasks in fetal ultrasound screening scans, aiding in the detection of potentially life-threatening conditions. However, these assessment methods can occasionally yield unreliable results. Advances in deep learning have opened up new avenues for automated measurements in fetal ultrasound, demonstrating human-level performance in various fetal ultrasound tasks. Nevertheless, the majority of these studies are retrospective in silico studies, with a limited number including African patients in their datasets. In this study we developed and prospectively assessed the performance of deep learning models for end-to-end automation of fetal biometry and amniotic fluid volume measurements. These models were trained using a newly constructed database of 172,293 de-identified Moroccan fetal ultrasound images, supplemented with publicly available datasets. the models were then tested on prospectively acquired video clips from 172 pregnant people forming a consecutive series gathered at four healthcare centers in Morocco. Our results demonstrate that the 95% limits of agreement between the models and practitioners for the studied measurements were narrower than the reported intra- and inter-observer variability among expert human sonographers for all the parameters under study. This means that these models could be deployed in clinical conditions, to alleviate time-consuming, repetitive tasks, and make fetal ultrasound more accessible in limited-resource environments.

Authors

  • Saad Slimani
    Deepecho, 10106, Rabat, Morocco. saad.slimani@deepecho.io.
  • Salaheddine Hounka
    Telecommunications Systems Services and Networks lab (STRS Lab), INPT, 10112, Rabat, Morocco.
  • Abdelhak Mahmoudi
    Deepecho, 10106, Rabat, Morocco.
  • Taha Rehah
    Deepecho, 10106, Rabat, Morocco.
  • Dalal Laoudiyi
    Ibn Rochd University Hospital, Hassan II University, 20100, Casablanca, Morocco.
  • Hanane Saadi
    Mohammed VI University Hospital, 60049, Oujda, Morocco.
  • Amal Bouziyane
    Université Mohammed VI des Sciences de la Santé, Hôpital Universitaire Cheikh Khalifa, 82403, Casablanca, Morocco.
  • Amine Lamrissi
    Ibn Rochd University Hospital, Hassan II University, 20100, Casablanca, Morocco.
  • Mohamed Jalal
    Ibn Rochd University Hospital, Hassan II University, 20100, Casablanca, Morocco.
  • Said Bouhya
    Ibn Rochd University Hospital, Hassan II University, 20100, Casablanca, Morocco.
  • Mustapha Akiki
    Abou Madi Radiology Clinic, 20060, Casablanca, Morocco.
  • Youssef Bouyakhf
    Deepecho, 10106, Rabat, Morocco.
  • Bouabid Badaoui
    Laboratory of Biodiversity, Ecology, and Genome, Faculty of Sciences, Department of Biology, Mohammed V University in Rabat, Rabat, Morocco.
  • Amina Radgui
    Telecommunications Systems Services and Networks lab (STRS Lab), INPT, 10112, Rabat, Morocco.
  • Musa Mhlanga
    Radboud Institute for Molecular Life Sciences, Epigenomics & Single Cell Biophysics, 6525 XZ, Nijmegen, the Netherlands.
  • El Houssine Bouyakhf
    Deepecho, 10106, Rabat, Morocco.