Digital cytology part 2: artificial intelligence in cytology: a concept paper with review and recommendations from the American Society of Cytopathology Digital Cytology Task Force.

Journal: Journal of the American Society of Cytopathology
Published Date: Dec 3, 2023

Abstract

Digital cytology and artificial intelligence (AI) are gaining greater adoption in the cytology laboratory. However, peer-reviewed real-world data and literature are lacking in regard to the current clinical landscape. The American Society of Cytopathology in conjunction with the International Academy of Cytology and the Digital Pathology Association established a special task force comprising 20 members with expertise and/or interest in digital cytology. The aim of the group was to investigate the feasibility of incorporating digital cytology, specifically cytology whole slide scanning and AI applications, into the workflow of the laboratory. In turn, the impact on cytopathologists, cytologists (cytotechnologists), and cytology departments were also assessed. The task force reviewed existing literature on digital cytology, conducted a worldwide survey, and held a virtual roundtable discussion on digital cytology and AI with multiple industry corporate representatives. This white paper, presented in 2 parts, summarizes the current state of digital cytology and AI practice in global cytology practice. Part 1 of the white paper is presented as a separate paper which details a review and best practice recommendations for incorporating digital cytology into practice. Part 2 of the white paper presented here provides a comprehensive review of AI in cytology practice along with best practice recommendations and legal considerations. Additionally, the cytology global survey results highlighting current AI practices by various laboratories, as well as current attitudes, are reported.

Authors

  • David Kim
    Department of Biochemistry, University of Washington, Seattle, WA 98105.
  • Kaitlin E Sundling
    The Wisconsin State Laboratory of Hygiene and Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
  • Renu Virk
    Department of Pathology and Cell Biology, Columbia University, New York, New York.
  • Michael J Thrall
    Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas.
  • Susan Alperstein
    Department of Pathology and Laboratory Medicine, New York Presbyterian-Weill Cornell Medicine, New York, New York.
  • Marilyn M Bui
    Department of Pathology, Moffitt Cancer Center, Tampa, FL, USA.
  • Heather Chen-Yost
    Department of Pathology, Michigan Medicine, Ann Arbor, Michigan.
  • Amber D Donnelly
    Diagnostic Cytology Education, University of Nebraska Medical Center, College of Allied Health Professions, Omaha, Nebraska.
  • Oscar Lin
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA, lino@mskcc.org.
  • Xiaoying Liu
    Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
  • Emilio Madrigal
    Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.
  • Pamela Michelow
    Cytology Unit, Department of Anatomical Pathology, Faculty of Health Science, National Health Laboratory Service, University of the Witwatersrand, Johannesburg, South Africa.
  • Fernando C Schmitt
    Department of Pathology, Medical Faculty of Porto University, Porto, Portugal.
  • Philippe R Vielh
    Department of Pathology, Medipath and American Hospital of Paris, Paris, France.
  • Maureen F Zakowski
    Department of Pathology, Mount Sinai Medical Center, New York, New York.
  • Anil V Parwani
    Department of Pathology, The Ohio State University Wexner Medical Centre, Columbus, OH, USA.
  • Elizabeth Jenkins
    American Society of Cytopathology, Wilmington, Delaware.
  • Momin T Siddiqui
    Department of Pathology and Laboratory Medicine, New York Presbyterian-Weill Cornell Medicine, New York, New York.
  • Liron Pantanowitz
    Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Zaibo Li
    Deparment of Pathology, The Ohio State Unversity, Columbus, Ohio, USA.

Keywords

External Resources

Popular Topics
Recent Journals