Prediction of Human Microbe-Drug Association based on Layer Attention Graph Convolutional Network.

Journal: Current medicinal chemistry
Published Date: Jan 1, 2024

Abstract

UNLABELLED: Human microbes are closely associated with a variety of complex diseases and have emerged as drug targets. Identification of microbe-related drugs is becoming a key issue in drug development and precision medicine. It can also provide guidance for solving the increasingly serious problem of drug resistance enhancement in viruses.

Authors

  • Jia Qu
    National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China. Electronic address: jia.qu@163.com.
  • Jie Ni
    School of Mechanical Engineering, University of Science and Technology Beijing, Beijing, China.
  • Tong-Guang Ni
    School of Computer Science and Artificial Intelligence & Aliyun School of Big Data, Changzhou University, Changzhou, 213164, China.
  • Ze-Kang Bian
    School of AI & Computer Science, Jiangnan University, Wuxi, 214122, China.
  • Jiu-Zhen Liang
    School of Computer Science and Artificial Intelligence & Aliyun School of Big Data, Changzhou University, Changzhou, 213164, China.

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