Enhancing automated strabismus classification with limited data: Data augmentation using StyleGAN2-ADA.

Journal: PloS one
PMID:

Abstract

In this study, we propose a generative data augmentation technique to overcome the challenges of severely limited data when designing a deep learning-based automated strabismus diagnosis system. We implement a generative model based on the StyleGAN2-ADA model for system design and assess strabismus classification performance using two classifiers. We evaluate the capability of our proposed method against traditional data augmentation techniques and confirm a substantial enhancement in performance. Furthermore, we conduct experiments to explore the relationship between the diagnosis agreement among ophthalmologists and the generation performance of the generative model. Beyond FID, we validate the generative samples on the classifier to establish their practicality. Through these experiments, we demonstrate that the generative model-based data augmentation improves overall quantitative performance in scenarios of extreme data scarcity and effectively mitigates overfitting issues during deep learning model training.

Authors

  • Jaehan Joo
    Department of Electronics Engineering, Pusan National University, Busan, Republic of Korea.
  • Sang Yoon Kim
    Department of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
  • Donghwan Kim
    Department of Physical Medicine & Rehabilitation, Kyung Hee University Hospital at Gangdong, Seoul 02447, Korea.
  • Ji-Eun Lee
    Department of Neurology (J.-E.L., I.Y., H.-N.S., I.-Y.B., J.-W.C., O.Y.B., G.-M.K., W.-K.S.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Republic of Korea.
  • Seung Min Lee
    Department of Ophthalmology, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.
  • Su Youn Suh
    Department of Ophthalmology, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.
  • Su-jin Kim
    Department of Surgery, Seoul National University Hospital and College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, Korea.
  • Suk Chan Kim
    Department of Electronics Engineering, Pusan National University, Busan, Republic of Korea.