High-throughput analysis of hazards in novel food based on the density functional theory and multimodal deep learning.

Journal: Food chemistry
PMID:

Abstract

The emergence of cultured meat presents the potential for personalized food additive manufacturing, offering a solution to address future food resource scarcity. Processing raw materials and products in synthetic food products poses challenges in identifying hazards, impacting the entire industrial chain during the industry's further evolution. It is crucial to examine the correlation of biological information at different levels and to reveal the temporal dynamics jointly. Proposed active prevention method includes four aspects: (i) Investigating the molecular-level mechanism underlying the binding and dissociation of hazards with proteins represents a novel approach to mitigate matrix effect. (ii) Identifying distinct fragments is a pivotal advancement toward developing a novel screening strategy for hazards throughout the food chain. (iii) Designing an artificial intelligence model-based approach to acquire multi-dimensional histology data also holds significant potential for various applications. (iv) Integrating multimodal data is a practical approach to enhance evaluation and feedback control accuracy.

Authors

  • Lin Shi
    Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Shatin, China.
  • Wei Jia
    Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
  • Rong Zhang
    Internal Medicine - Cardiology Division, UT Southwestern, Dallas, TX, USA.
  • Zibian Fan
    School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an 710021, China. jiawei@sust.edu.cn.
  • Wenwen Bian
    Agricultural Product Processing and Inspection Center, Shaanxi Testing Institute of Product Quality Supervision, Xi'an, Shaanxi, China.
  • Haizhen Mo
    School of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an 710021, China; Shaanxi Research Institute of Agricultural Products Processing Technology, Xi'an 710021, China. Electronic address: mohz@sust.edu.cn.