MotGen: a closed-loop bacterial motility control framework using generative adversarial networks.

Journal: Bioinformatics (Oxford, England)
PMID:

Abstract

MOTIVATION: Many organisms' survival and behavior hinge on their responses to environmental signals. While research on bacteria-directed therapeutic agents has increased, systematic exploration of real-time modulation of bacterial motility remains limited. Current studies often focus on permanent motility changes through genetic alterations, restricting the ability to modulate bacterial motility dynamically on a large scale. To address this gap, we propose a novel real-time control framework for systematically modulating bacterial motility dynamics.

Authors

  • BoGeum Seo
    Department of Mechanical Engineering, Seoul National University, 08826 Seoul, Republic of Korea.
  • Dohee Lee
  • Heungjin Jeon
  • Junhyoung Ha
  • SeungBeum Suh