Enriching the FIDEO ontology with food-drug interactions from online knowledge sources.

Journal: Journal of biomedical semantics
Published Date:

Abstract

The increasing number of articles on adverse interactions that may occur when specific foods are consumed with certain drugs makes it difficult to keep up with the latest findings. Conflicting information is available in the scientific literature and specialized knowledge bases because interactions are described in an unstructured or semi-structured format. The FIDEO ontology aims to integrate and represent information about food-drug interactions in a structured way. This article reports on the new version of this ontology in which more than 1700 interactions are integrated from two online resources: DrugBank and Hedrine. These food-drug interactions have been represented in FIDEO in the form of precompiled concepts, each of which specifies both the food and the drug involved. Additionally, competency questions that can be answered are reviewed, and avenues for further enrichment are discussed.

Authors

  • Rabia Azzi
    Univ. Bordeaux, Inserm, BPH, U1219, F-33000, Bordeaux, France.
  • Georgeta Bordea
    Team ERIAS, BPH INSERM 1219, Univ. Bordeaux, F-33000, Bordeaux, France.
  • Romain Griffier
    Department of Public Health, Faculty of medicine, University of Bordeaux, Bordeaux, France.
  • Jean Noël Nikiema
    Department of Management, Evaluation and Health Policy, School of Public Health, Université de Montréal, Québec, Canada.
  • Fleur Mougin
    Université Bordeaux, ISPED, Centre INSERM U897, ERIAS, France.