Prediction of naloxone dose in opioids toxicity based on machine learning techniques (artificial intelligence).

Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences
PMID:

Abstract

BACKGROUND: Treatment management for opioid poisoning is critical and, at the same time, requires specialized knowledge and skills. This study was designed to develop and evaluate machine learning algorithms for predicting the maintenance dose and duration of hospital stay in opioid poisoning, in order to facilitate appropriate clinical decision-making.

Authors

  • Seyed Ali Mohtarami
    Department of Computer Engineering and Information Technology (PNU), Tehran, Iran.
  • Babak Mostafazadeh
    Toxicological Research Center, Excellence Center of Clinical Toxicology, Department of Clinical Toxicology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Shahin Shadnia
    Toxicological Research Center, Excellence Center of Clinical Toxicology, Department of Clinical Toxicology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: shahin1380@gmail.com.
  • Mitra Rahimi
    Toxicological Research Center, Excellence Center of Clinical Toxicology, Department of Clinical Toxicology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Peyman Erfan Talab Evini
    Toxicological Research Center, Excellence Center of Clinical Toxicology, Department of Clinical Toxicology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Maral Ramezani
    Department of Pharmacology, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
  • Hamed Borhany
    Toxicological Research Center, Department of Clinical Toxicology, Excellence Center of Clinical Toxicology, Loghman Hakim University Hospital Poison Center, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran.
  • Mobin Fathy
    Students Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Hamidreza Eskandari
    Toxicological Research Center, Department of Clinical Toxicology, Excellence Center of Clinical Toxicology, Loghman Hakim University Hospital Poison Center, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran.