Digital Imaging and AI Pre-classification in Hematology.

Journal: Clinics in laboratory medicine
Published Date:

Abstract

A leukocyte differential of peripheral blood can be performed using digital imaging coupled with cellular pre-classification by artificial neural networks. Platelet and erythrocyte morphology can be assessed and counts estimated. Systems from a single vendor have been used in clinical practice for several years, with other vendors' systems, in a development. These systems perform comparably to traditional manual optical microscopy, however, it is important to note that they are designed and intended to be operated by a trained morphologist. These systems have several benefits including increased standardization, efficiency, and remote-review capability.

Authors

  • Kelly A Bowers
    Cleveland Clinic, Robert. J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland, Ohio, USA.
  • Megan O Nakashima
    Department of Pathology and Laboratory Medicine, Cleveland Clinic, 9500 Euclid Avenue L30, Cleveland, OH 44195, USA. Electronic address: nakashm@ccf.org.