AI Medical Compendium Journal:
Asian Pacific journal of tropical medicine

Showing 1 to 10 of 16 articles

Natural compounds and extracts from Mexican medicinal plants with anti-leishmaniasis activity: An update.

Asian Pacific journal of tropical medicine
Leishmaniasis is considered as an emerging, uncontrolled disease and is endemic in 98 countries. Annually, about 2 million cases of cutaneous and 500000 cases of visceral-type leishmaniasis are recorded and 60000 persons died from the disease. In Mex...

Reverse effect of curcumin on CDDP-induced drug-resistance via Keap1/p62-Nrf2 signaling in A549/CDDP cell.

Asian Pacific journal of tropical medicine
OBJECTIVE: To assess the effect of curcumin on CDDP-induced drug resistance and explore the underlying molecular mechanism through Nrf2 system and autophagy pathway.

Pharmacological evaluation of smooth muscle relaxant and cardiac-modulation potential of Phyla nodiflora in ex-vivo and in-vivo experiments.

Asian Pacific journal of tropical medicine
OBJECTIVE: To investigate the pharmacological basis of its uses of Phyla nodiflora (P. nodiflora) for the treatment of anomalies predominantly by smooth muscle containing tissues such as gastrointestinal/vascular/broncho spasm and cardiovascular modu...

Regulating effect of glycyrrhetinic acid on bronchial asthma smooth muscle proliferation and apoptosis as well as inflammatory factor expression through ERK1/2 signaling pathway.

Asian Pacific journal of tropical medicine
OBJECTIVE: To study the influence of glycyrrhetinic acid (GA) on bronchial asthma (BA) smooth muscle proliferation and apoptosis as well as inflammatory factor expression and its molecular mechanism.

Phytochemical analysis and biological activities of Hertia cheirifolia L. roots extracts.

Asian Pacific journal of tropical medicine
OBJECTIVE: To test the antioxidant, antimicrobial and α-glucosidase inhibitory activities of the roots extracts from Hertia cheirifolia (H. cheirifolia) L.

Comparative molecular docking studies of lupeol and lupenone isolated from Pueraria lobata that inhibits BACE1: Probable remedies for Alzheimer's disease.

Asian Pacific journal of tropical medicine
OBJECTIVE: To discover lead lupane triterpenoid's potential isolated from Pueraria lobata roots against β-site amyloid precursor protein cleaving enzyme 1 (BACE1), which serve as a rate limiting step in amyloid beta (Aβ) production altering the cours...

Antileishmanial activities of caffeic acid phenethyl ester loaded PLGA nanoparticles against Leishmania infantum promastigotes and amastigotes in vitro.

Asian Pacific journal of tropical medicine
OBJECTIVE: To investigate and compare the antileishmanial effects of CAPE and (CAPE) on Leishmania infantum (L. infantum) promastigotes and amastigotes in vitro.

First isolation of glutinol and a bioactive fraction with good anti-inflammatory activity from n-hexane fraction of Peltophorum africanum leaf.

Asian Pacific journal of tropical medicine
OBJECTIVE: To investigate the anti-inflammatory activity of different fractions and glutinol (isolated compound), using nitric oxide synthase and cyclooxygenase (COX) inhibition as an indication of anti-inflammatory activity.

Neuroprotective effect of Spilanthes acmella Murr. on pesticide-induced neuronal cells death.

Asian Pacific journal of tropical medicine
OBJECTIVE: To investigate protective effects of Spilanthes acmella (S. acmella) Murr. extracts against pesticide-induced neuronal cells death and to elucidate the underlying molecular mechanism in dopaminergic (SH-SY5Y) cells lines.

Adipose tissue-derived stem cells ameliorates dermal fibrosis in a mouse model of scleroderma.

Asian Pacific journal of tropical medicine
OBJECTIVE: To investigate the therapeutic potential of adipose-derived stem cells (ADSCs) for limited cutaneous scleroderma (LS) in mouse models.