AIMC Journal:
Biomarker research

Showing 1 to 3 of 3 articles

Microbiome multi-omics analysis reveals novel biomarkers and mechanisms linked with CD etiopathology.

Biomarker research
BACKGROUND: The gut microbiome plays a key role in the development of inflammatory bowel disease (IBD), as imbalances in microbial composition are associated with immune dysfunction. However, the specific mechanisms by which certain microorganisms co...

A plasma 9-microRNA signature for lung cancer early detection: a multicenter analysis.

Biomarker research
Lung cancer remains the leading cause of cancer-related deaths worldwide. Low-dose computed tomography (LD-CT) screening, combined with effective minimally invasive molecular testing such circulating microRNA, has the potential to reduce the burden o...

Insights into KMT2A rearrangements in acute myeloid leukemia: from molecular characteristics to targeted therapies.

Biomarker research
Acute myeloid leukemia (AML) with KMT2A rearrangements (KMT2A-r) represents a highly aggressive and prognostically unfavorable subtype of leukemia, often resistant to standard treatments and associated with high relapse rates. KMT2A-r, found in 3-10%...