AI Medical Compendium Journal:
Frontiers in chemistry

Showing 1 to 10 of 25 articles

Establishment and evaluation of a UPLC-MS/MS method for simultaneous determination of bongkrekic acid and dehydroacetic acid in rice noodles.

Frontiers in chemistry
A UPLC-MS/MS method with one-step extraction and simultaneous determination of bongkrekic acid (BA) and dehydroacetic acid (DHA) in rice noodles has been established in this study for the first time. The extraction solvent consisted of a mixture of m...

Innovative determination of phytohormones in .

Frontiers in chemistry
INTRODUCTION: Aloe vera is widely known for its therapeutic properties, but concerns regarding the levels of phytohormones and their potential impact on human health highlight the need for advanced analytical techniques. This study aims to develop an...

Therapeutic potential of against monkeypox: antioxidant, anti-inflammatory, and computational insights.

Frontiers in chemistry
BACKGROUND: Monkeypox (Mpox) is a re-emerging zoonotic disease with limited therapeutic options, necessitating the exploration of novel antiviral agents. (turmeric) is a widely used medicinal plant known for its antioxidant and anti-inflammatory pro...

Research on detection methods of related substances and degradation products of the antitumor drug selpercatinib.

Frontiers in chemistry
BACKGROUND: Selpercatinib, a selective RET kinase inhibitor, is approved for treating various cancers with RET gene mutations such as RET-rearranged thyroid cancer and non-small cell lung cancer. The presence of process-related and degradation impuri...

Machine learning and molecular dynamics simulations predict potential TGR5 agonists for type 2 diabetes treatment.

Frontiers in chemistry
INTRODUCTION: Treatment of type 2 diabetes (T2D) remains a significant challenge because of its multifactorial nature and complex metabolic pathways. There is growing interest in finding new therapeutic targets that could lead to safer and more effec...

Machine learning and molecular docking prediction of potential inhibitors against dengue virus.

Frontiers in chemistry
INTRODUCTION: Dengue Fever continues to pose a global threat due to the widespread distribution of its vector mosquitoes, and . While the WHO-approved vaccine, Dengvaxia, and antiviral treatments like Balapiravir and Celgosivir are available, challe...

Evaluation of the anti-spasmodic activity of essential oils of fruits and its main chemical component "perillaldehyde" on intestinal smooth muscle contractions of rodents: and approaches.

Frontiers in chemistry
ETHNOPHARMACOLOGICAL RELEVANCE: In Moroccan traditional medicine, plants from the Apiaceae family are widely utilized in folk medicine to treat various diseases associated with the digestive system. plays an important role as an antispasmodic that h...

Sustainable nanomaterials: the role of Cyrene in optimising carbon nanotubes dispersion and filtration efficiency.

Frontiers in chemistry
This study focuses on the fabrication and characterisation of single-walled carbon nanotube (SWCNT) buckypapers and polyethersulfone (PES) flat-sheet membranes using Cyrene, aiming toevaluate its efficacy as a green solvent for these applications. Pr...

Covalent integration of polymers and porous organic frameworks.

Frontiers in chemistry
Covalent integration of polymers and porous organic frameworks (POFs), including metal-organic frameworks (MOFs), covalent organic frameworks (COFs) and hydrogen-bonded organic frameworks (HOFs), represent a promising strategy for overcoming the exis...

Phytochemical profiling and fractionation of extract versus silver nanoparticle-modified extract: assessment of photoprotective, anti-hemolytic, antibacterial, and anti-inflammatory properties.

Frontiers in chemistry
INTRODUCTION: This study investigates the synthesis of silver nanoparticles (Ag NPs) using Helianthemum lippii extract and evaluates their photoprotective, anti-hemolytic, antibacterial, and anti-inflammatory properties compared to various extract fr...