Frontiers in genetics
Jan 29, 2025
INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a rare but debilitating lung disease characterized by excessive fibrotic tissue accumulation, primarily affecting individuals over 50 years of age. Early diagnosis is challenging, and without inter...
Frontiers in genetics
Jan 29, 2025
Compound inference models are crucial for discovering novel drugs in bioinformatics and chemo-informatics. These models rely heavily on useful descriptors of chemical compounds that effectively capture important information about the underlying compo...
Frontiers in genetics
Jan 22, 2025
INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a severe chronic respiratory disease characterized by treatment challenges and poor prognosis. Identifying relevant biomarkers for effective early-stage risk prediction is therefore of critical imp...
Frontiers in genetics
Jan 15, 2025
INTRODUCTION: Due to its favorable traits-such as lower lignin content, higher oil concentration, and increased protein levels-the genetic improvement of yellow-seeded rapeseed has attracted more attention than other rapeseed color variations. Tradit...
Frontiers in genetics
Jan 15, 2025
BACKGROUND: Hepatocellular carcinoma (HCC) accounts for over 80% of primary liver cancers and is the third leading cause of cancer-related deaths worldwide. Hepatitis B virus (HBV) infection is the primary etiological factor. Disulfidptosis is a newl...
Frontiers in genetics
Jan 10, 2025
BACKGROUND: Depression, a prevalent chronic mental disorder, presents complexities and treatment challenges that drive researchers to seek new, precise therapeutic targets. Additionally, the potential connection between depression and cancer has garn...
Frontiers in genetics
Jan 8, 2025
BACKGROUND: Lung adenocarcinoma (LUAD) is a highly aggressive tumor with one of the highest morbidity and mortality rates in the world. Nucleotide metabolic processes are critical for cancer development, progression, and alteration of the tumor micro...
Frontiers in genetics
Jan 8, 2025
Cysteine S-carboxyethylation, a novel post-translational modification (PTM), plays a critical role in the pathogenesis of autoimmune diseases, particularly ankylosing spondylitis. Accurate identification of S-carboxyethylation modification sites is e...
Frontiers in genetics
Jan 8, 2025
Peanut is a vital source of protein, particularly in the tropical regions of Asian and African countries. About three-quarters of peanut production occurs worldwide in arid and semi-arid regions, making drought an important concern in peanut producti...
Frontiers in genetics
Jan 7, 2025
Recent advancements in deep learning, particularly large language models (LLMs), made a significant impact on how researchers study microbiome and metagenomics data. Microbial protein and genomic sequences, like natural languages, form a , enabling t...