AI Medical Compendium Journal:
Frontiers in genetics

Showing 31 to 40 of 44 articles

Probing lncRNA-Protein Interactions: Data Repositories, Models, and Algorithms.

Frontiers in genetics
Identifying lncRNA-protein interactions (LPIs) is vital to understanding various key biological processes. Wet experiments found a few LPIs, but experimental methods are costly and time-consuming. Therefore, computational methods are increasingly exp...

Heterogeneous Multi-Layered Network Model for Omics Data Integration and Analysis.

Frontiers in genetics
Advances in next-generation sequencing and high-throughput techniques have enabled the generation of vast amounts of diverse omics data. These big data provide an unprecedented opportunity in biology, but impose great challenges in data integration, ...

Integrating Computational Methods to Investigate the Macroecology of Microbiomes.

Frontiers in genetics
Studies in microbiology have long been mostly restricted to small spatial scales. However, recent technological advances, such as new sequencing methodologies, have ushered an era of large-scale sequencing of environmental DNA data from multiple biom...

Integrated Hypothalamic Transcriptome Profiling Reveals the Reproductive Roles of mRNAs and miRNAs in Sheep.

Frontiers in genetics
Early studies have provided a wealth of information on the functions of microRNAs (miRNAs). However, less is known regarding their functions in the hypothalamus involved in sheep reproduction. To explore the potential roles of hypothalamic messenger ...

Genomic Selection in Aquaculture: Application, Limitations and Opportunities With Special Reference to Marine Shrimp and Pearl Oysters.

Frontiers in genetics
Within aquaculture industries, selection based on genomic information (genomic selection) has the profound potential to change genetic improvement programs and production systems. Genomic selection exploits the use of realized genomic relationships a...

A Novel Protein Subcellular Localization Method With CNN-XGBoost Model for Alzheimer's Disease.

Frontiers in genetics
The disorder distribution of protein in the compartment or organelle leads to many human diseases, including neurodegenerative diseases such as Alzheimer's disease. The prediction of protein subcellular localization play important roles in the unders...

FLOating-Window Projective Separator (FloWPS): A Data Trimming Tool for Support Vector Machines (SVM) to Improve Robustness of the Classifier.

Frontiers in genetics
Here, we propose a heuristic technique of data trimming for SVM termed (), tailored for personalized predictions based on molecular data. This procedure can operate with high throughput genetic datasets like gene expression or mutation profiles. Its...

Developmental Dioxin Exposure Alters the Methylome of Adult Male Zebrafish Gonads.

Frontiers in genetics
2,3,7,8-Tetrachlorodibenzo--dioxin (TCDD) is a persistent environmental toxicant and endocrine disrupting compound with reproductive and developmental effects in humans and model organisms, including zebrafish. Our previous microarray and histologica...

Genomic Selection and Use of Molecular Tools in Breeding Programs for Indigenous and Crossbred Cattle in Developing Countries: Current Status and Future Prospects.

Frontiers in genetics
Genomic selection (GS) has resulted in rapid rates of genetic gains especially in dairy cattle in developed countries resulting in a higher proportion of genomically proven young bulls being used in breeding. This success has been undergirded by well...