AI Medical Compendium Journal:
Hospital pharmacy

Showing 11 to 20 of 47 articles

In Vitro Assessment for Dose Preparation and Simulated Administration of Azithromycin Suspensions via Enteral Feeding Tubes.

Hospital pharmacy
Administration of medication via enteral feeding tubes (EFT) is common in cases where patients are unable to swallow the dosage form or a patient is intubated. The SARS-CoV-2 (COVID-19, coronavirus disease 2019) epidemic created a need to rapidly eva...

Hidden Fluids in Plain Sight: Identifying Intravenous Medication Classes as Contributors to Intensive Care Unit Fluid Intake.

Hospital pharmacy
Fluid stewardship targets optimal fluid management to improve patient outcomes. Intravenous (IV) medications, flushes, and blood products, collectively referred to as hidden fluids, contribute to fluid intake in the intensive care unit (ICU). The im...

An Exploratory Study of a New Vancomycin Eye Drops Formulation for Extemporaneous Compounding.

Hospital pharmacy
PURPOSE: Compounded eye drop solutions of vancomycin hydrochloride have important clinical applications, such as postoperative antimicrobial prophylaxis and bacterial keratitis. There exists a plethora of data to support the use of various liquid veh...

Stability of 4 Intravenous Drug Formulations in Prefilled Syringes Stored Frozen for Up to 60 Days.

Hospital pharmacy
Prefilled drug syringe use may reduce the cost of routine antibiotic drug delivery. Storage of prefilled syringes frozen (-20°C) or refrigerated (4°C-5°C), can optimize the use of robotic syringe filling systems if acceptable stability data is gathe...

Chemical Degradation of Intravenous Chemotherapy Agents and Opioids by a Novel Instrument.

Hospital pharmacy
To assess chemical degradation of various liquid chemotherapy and opioid drugs in the novel RxDestruct™ instrument. Intravenous (IV) drug solutions for chemotherapy and pain management were prepared using 0.9% normal saline in Excel bags to a final...

Effects of CYP2C19*17 Genetic Polymorphisms on the Steady-State Concentration of Diazepam in Patients With Alcohol Withdrawal Syndrome.

Hospital pharmacy
Diazepam is one of the most widely prescribed tranquilizers for the therapy of alcohol withdrawal syndrome (AWS), which includes the symptoms of anxiety, fear, and emotional tension. However, diazepam therapy often turns out to be ineffective, and s...

Stability of Ampicillin in Normal Saline Following Refrigerated Storage and 24-Hour Pump Recirculation.

Hospital pharmacy
OBJECTIVE: Use of ampicillin in outpatient parenteral antimicrobial therapy (OPAT) has historically been complicated by frequent dosing and limited stability. The purpose of this study was to evaluate stability of ampicillin using high-pressure liqui...

Correlation of Measured and Estimated Creatinine Clearance in Hospitalized Elderly Patients: A Retrospective Cohort Study.

Hospital pharmacy
Accurate assessment of renal function is essential in hospitalized elderly patients. Few studies have examined the accuracy of Cockcroft-Gault (C-G) estimates of creatinine clearance (CrCl) compared with measured clearance in these patients. The ob...

Is P&T Ready to Add Rapid Cycle Analytics to Formulary?

Hospital pharmacy
The intent of this article is to evaluate a novel approach, using rapid cycle analytics and real world evidence, to optimize and improve the medication evaluation process to help the formulary decision making process, while reducing time for clinici...

Chemical and Physical Stability of an Admixture Containing Cefepime and Vancomycin in Lactated Ringer Solution.

Hospital pharmacy
To evaluate the chemical and physical stability of an admixture containing cefepime and vancomycin in a single volume of lactated Ringer solution at refrigerated temperatures. Cefepime 2000 mg and vancomycin 1000 mg were, respectively, reconstitute...