AI Medical Compendium Journal:
Iranian journal of pharmaceutical research : IJPR

Showing 1 to 10 of 62 articles

Evaluating the Inhibitory Effects of Probiotic Bacteria and Propolis Extracts on the Growth and Histopathological Changes in Gastric Tissues of Challenged Wistar Rats.

Iranian journal of pharmaceutical research : IJPR
BACKGROUND: is a significant contributor to a range of gastrointestinal conditions, with conventional treatment methods primarily relying on antibiotics. However, the rise of antibiotic-resistant strains has necessitated the exploration of alternati...

The Application of Machine Learning in Predicting the Permeability of Drugs Across the Blood Brain Barrier.

Iranian journal of pharmaceutical research : IJPR
The inefficiency of some medications to cross the blood-brain barrier (BBB) is often attributed to their poor physicochemical or pharmacokinetic properties. Recent studies have demonstrated promising outcomes using machine learning algorithms to pred...

Advancements and Applications of Artificial Intelligence in Pharmaceutical Sciences: A Comprehensive Review.

Iranian journal of pharmaceutical research : IJPR
Artificial intelligence (AI) has revolutionized the pharmaceutical industry, improving drug discovery, development, and personalized patient care. Through machine learning (ML), deep learning, natural language processing (NLP), and robotic automation...

Antiproliferative and Pro-apoptotic Activities of vent. Leaves on the Human Breast Adenocarcinoma Cell Line (MCF-7).

Iranian journal of pharmaceutical research : IJPR
BACKGROUND: Breast cancer is the most common cancer among women worldwide, impacting not only the patients but also their families and communities. vent. is a plant endemic to Mexico, traditionally used in Zapotec medicine for the treatment of cance...

Inhibitory Effects of L. Extract on the Female Hormones Based on Bioautography-HPTLC-MS.

Iranian journal of pharmaceutical research : IJPR
BACKGROUND: Hormonal imbalances related to women's health, physical activity, and fluctuations are prevalent metabolic disorders in several nations and have significantly impacted women's health for an extended period. The application of individual o...

A Preliminary Study to Evaluate the Immune Response to a Booster Dose of the Adult Tetanus-Diphtheria Vaccine (Td) Available in Iran.

Iranian journal of pharmaceutical research : IJPR
BACKGROUND: Despite the availability of tetanus-diphtheria (TD) vaccines in Iran, the seroconversion rate of these products as a booster dose is unknown.

Establishment of an HPLC Fingerprint and Cluster Analysis for Miao Ethnic Medicine .

Iranian journal of pharmaceutical research : IJPR
, a traditional Miao medicine, is commonly used by the renowned national-level Chinese Traditional Medicine practitioner Zhengshi Wu for the treatment of diarrhea due to its strong antioxidative, anti-inflammatory, and antidiarrheal effects. This stu...

Screening and Identification of DNA Nanostructure Aptamer Using the SELEX Method for ‎Detection of Epsilon Toxin.

Iranian journal of pharmaceutical research : IJPR
BACKGROUND: Epsilon toxin (ETX), produced by , is one of the most potent toxins known, with a lethal potency approaching that of botulinum neurotoxins. Epsilon toxin is responsible for enteritis. Therefore, the development of rapid and simple methods...

Leaf Extract-Induced Apoptosis in the MCF-7 Breast Cancer Cell Line by Increasing Intracellular Oxidative Stress.

Iranian journal of pharmaceutical research : IJPR
BACKGROUND: is one of the plants used in the diet of Iranian people. Previous studies have investigated the antioxidant and antibacterial effects of this plant extract, but no study has been conducted on its anticancer properties.

Integration of Machine Learning and Structural Analysis for Predicting Peptide Antibiofilm Effects: Advancements in Drug Discovery for Biofilm-Related Infections.

Iranian journal of pharmaceutical research : IJPR
BACKGROUND: The rise of antibiotic resistance has become a major concern, signaling the end of the golden age of antibiotics. Bacterial biofilms, which exhibit high resistance to antibiotics, significantly contribute to the emergence of antibiotic re...