AI Medical Compendium Journal:
Journal of mass spectrometry and advances in the clinical lab

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A high-throughput LC-MS/MS assay for piperaquine from dried blood spots: Improving malaria treatment in resource-limited settings.

Journal of mass spectrometry and advances in the clinical lab
BACKGROUND: Malaria is a parasitic disease that affects many of the poorest economies, resulting in approximately 241 million clinical episodes and 627,000 deaths annually. Piperaquine, when administered with dihydroartemisinin, is an effective drug ...

Development and Validation of a Novel LC-MS/MS Assay for C-Peptide in Human Serum.

Journal of mass spectrometry and advances in the clinical lab
INTRODUCTION: C-peptide is used as a marker of endogenous insulin secretion in the assessment of residual β-cell function in diabetes and in the diagnostic workup of hypoglycemia. Previously developed LC-MS/MS methods to quantify serum concentrations...