AI Medical Compendium Journal:
Polymers

Showing 21 to 27 of 27 articles

Oral Delivery of Curcumin Polymeric Nanoparticles Ameliorates CCl₄-Induced Subacute Hepatotoxicity in Wistar Rats.

Polymers
Curcumin is the major bioactive compound of , an important medicinal plant used in traditional herbal formulations since ancient times. In the present study, we report that curcumin nanoparticles (ηCur) protects Wistar rats against carbon tetrachlori...

Synthesis of Quaternary Ammonium Salts of Chitosan Bearing Halogenated Acetate for Antifungal and Antibacterial Activities.

Polymers
In this paper, quaternary ammonium salts of chitosan bearing halogenated acetate, including ,,-trimethyl chitosan chloroacetate (TMCSC), ,,-trimethyl chitosan dichloroacetate (TMCSDC), ,,-trimethyl chitosan trichloroacetate (TMCSTC), and ,,-trimethyl...

PLGA Microspheres Loaded with β-Cyclodextrin Complexes of Epigallocatechin-3-Gallate for the Anti-Inflammatory Properties in Activated Microglial Cells.

Polymers
Although epigallocatechin-3-gallate (EG) is well-known as a potent antioxidant and free radical scavenger for neurodegenerative diseases, it still has disadvantages that reduce its treatment effectiveness due to low bioavailability, slow absorption, ...

pH-Sensitive Micelles Based on Star Copolymer Ad-(PCL-b-PDEAEMA-b-PPEGMA)₄ for Controlled Drug Delivery.

Polymers
Enhancing drug loading efficacy and stability of polymeric micelles remains a grand challenge. Here we develop adamantane-based star copolymers adamantane-[poly(ε-caprolactone)--poly(2-(diethylamino)ethyl methacrylate)--poly(poly(ethylene glycol) met...

Antioxidant Activity and Antifungal Activity of Chitosan Derivatives with Propane Sulfonate Groups.

Polymers
We successfully synthesized the water-soluble chitosan derivatives propane sulfonated chitosan (PSCS) and dipropane sulfonated chitosan (DPSCS) in this paper. These derivatives were characterized by FTIR, ¹H NMR, and C NMR. Moreover, the antioxidant ...

Engineering Polyzwitterion and Polydopamine Decorated Doxorubicin-Loaded Mesoporous Silica Nanoparticles as a pH-Sensitive Drug Delivery.

Polymers
Multifunctional drug carriers have great applications in biomedical field. In this study, we introduced both polydopamine (PDA) and zwitterionic polymer of poly(3-(3-methacrylamidopropyl-(dimethyl)-ammonio)propane-1-sulfonate) (PSPP) onto the surface...

The Discovery of an Iridium(III) Dimer Complex as a Potent Antibacterial Agent against Non-Replicating Mycobacterium smegmatis.

Polymers
Novel agents are urgently needed to rapidly kill drug-resistant . Noble metal complexes, particularly polypyridyl iridium complexes serving as therapeutic agents, have attracted considerable interest recently, due to their significant cytotoxic or an...