AIMC Journal:
Translational cancer research

BACKGROUND: Hypoxia contributes to the proliferation, migration, and chemotherapy resistance of lung adenocarcinoma (LUAD). This study aimed to identify hypoxia-related genes (HRGs) in LUAD that were positively correlated with hypoxia-inducible facto...

BACKGROUND: Uterine sarcoma is a gynecological mesenchymal tumor with an elusive pathogenesis. The uterine leiomyosarcoma (LMS) is the most common subtype of uterine sarcoma. LMS is a highly aggressive tumor with a poor prognosis. The genomic landsca...

BACKGROUND: Colorectal cancer (CRC) is one of the most common malignancies globally and a major cause of cancer-related deaths. In the molecular diagnosis of CRC, microsatellite instability (MSI) status and mutations in genes such as , , and are imp...

BACKGROUND: Pancreatic cancer, a highly malignant tumor with poor prognosis, lacks effective early diagnosis and treatment strategies. Sphingolipids have emerged as key players in tumorigenesis, with certain sphingolipid-related genes linked to patie...

BACKGROUND: Cervical cancer (CC) is one of the most common gynecological malignancies. Previous studies have shown that the prognosis of CC is affected by many factors. Our study aimed to identify key prognostic factors and use machine learning and d...

BACKGROUND: Nervous system-cancer interactions can regulate tumorigenesis, invasion, and metastasis. However, specific biomarkers for targeting neuron synapse in colorectal cancer (CRC) remain unexplored. This study aims to develop a neuronal synapse...