AIMC Topic: Receptors, Antigen, T-Cell

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PiTE: TCR-epitope Binding Affinity Prediction Pipeline using Transformer-based Sequence Encoder.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Accurate prediction of TCR binding affinity to a target antigen is important for development of immunotherapy strategies. Recent computational methods were built on various deep neural networks and used the evolutionary-based distance matrix BLOSUM t...